I'm in the middle of testing this opener on an industrial scale. I have 4 different profiles up in various cities. I sent this version of the opener 64 times so far:
1."Hey, I would remove the second pic in your profile."
2."I was just kidding, I though you were adorable and had to say hi.
The result was 34 replies or 53%, higher than any other message I've sent. However, about half the messages are negative, this opener really freaks them out, as our good friend Asianredneck said.
Example response:
"Hahaha that was a terrible first liner! i was like, 'whats wrong with my tattoo?? is my face crooked? Anyway my toga night photo is much more atrocious whats the matter with him?'
this all went through my head when reading that at Publix. im slightly in a state of perpetual perplexion. heh.
i do appreciate being called adorable though, thanks.

"
My favorite response:
"i would remove all the pictures in yours you cancer stick sucking prick. do you like sucking cock just as much? figures. guys who have pictures like that in their profile surrounded my huge hairy red head men are gay - hahaha sucks for you"
The beauty of it is that after they curse you out because they're insecure about their looks and then realize you were not insulting you, they feel horrible and try to seek approval. It gets responses, but I still have to figure out if it gets numbers. Obviously, results are specific to me, try it yourself.