I can never seem to land anything when approaching girls at a club, who aren't on the dance floor. however its still loud enough that you have to break eye contact to speak. i never know what to talk about, i can open fairly easy but after 15/30sec i just get boring.

what are some interesting topics of conversation to have? also how should i act via social value in a club. usually i try to never stand still unless im having a conversation however ive been told by my male friends who don't approach very often that as i pace the club i look like a predator, do girls view me as this to?
Thanks

Cultivate an interesting life. Meet people and have sexual adventures. Then when you step in the club or anywhere else, your dominant persona will edge out everyone except for those above your pay grade so to speak. In other words, almost everyone. The dudes with the huge muscles, the dudes with the huge bankrolls, they mean jack shit when compared to a guy with a dominant persona such as the one that can be developed through living a truly social, truly abundant lifestyle.

What's FAR more important than the topic is your energy and vibe. If you have low key energy and the wrong vibe then picking up in a high energy club environment will be difficult. If you have great energy then a simple hi would be fine.

Personally I use situational openers (e.g. something they're wearing) and turn it into something funny.

I agree with your friends - pacing the club too much looks weird. Do so once or twice an hour maybe, but if you're continually walking a few people may notice and get a bit weirded out.

then what, after i open and get her attention i get boring. its to early to move her/escalate. so what do i talk about.

USUALLY I make a couple of jokes, make her laugh, make her tell me something interesting about herself.

What you say in a high energy setting is not extremely important. You want to give her an EXPERIENCE. You want to get her emotions going. Play thumb wars. Bounce her to different locations in the bar OR another bar entirely. Give her a fun challenge. Do something interesting. Tell her about the most amazing weekend you had, even if in reality it was pretty boring.

Always speak for yourself while gaming. Never, speak to impress her, talk about things that will entertain you. If your opener and body language/tonality are correct, she'll engage in the convo.

If not, just remember, you are doing this for YOU. The conversation was your choice to start, and it should be your choice to finish.

Can you carry a conversation with someone you aren't gaming? Such as a professor, friend, or family member?
If you answer yes to that, but can't carry conversation with someone you're gaming, you are over thinking it.