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So you got a girl to reply to the opener and she gives you a one word reply( ex: M&Ms)
Where do you go from here?
Do you make up a statement based on her answer to create some interest or transition to something from her profile?
Well I would say to show her some indifference. Challenge her on her answer. Most guys agree with the girl in hopes to forming some kind of "bond". I would also tell her something like "yeah, after looking at your pics a little more, you do seem like a peanut m & m kind of girl

" its a cold read and she will wonder what you mean by that. Have fun. Neither of you two are invested and you have to be willing to lose the girl. This will help you also to transition to a dhv story in which you can say she looks like your friend sarah who loves eating peanut m & m's. See just having fun and being cocky funny.
I personally hate when they give you one word responses after you send them a long well thought out opening message. She could just be very boring or not very confident in herself. So try doing what I suggested and if it doesn't work, theres only 3 billion more to go.
Cheers my friend.