So i was just wondering can i still use routines, techniques, openers, etc. if i'm a lesbian? Will the girls react the same as if i were a dude or do they have different "switches" then if i were a man? If this is the case, should i just stick with lesbians or try this stuff on straight women too?

Im not terribly sure about if the tactics would be exactly the same, but if I were you I would just go for it with everyone.. because alot of the info I am seeing tells us to be confident and to open everyone. If your getting interest from straight women I would try to close them also. As long as your not to agressive, whats the worst that could happen.. You know

I am a girl and I have had success with a lot of this stuff. That said, I am straight so guys respond to some stuff, but not all. So I would say learn as much as you can but question everything and learn by trial and error. Dre is a lesbian on the forum that I think can help you more than I can.

Thanks you guys i appreciate it, i guess this is going to be a trail and error sort of thing. I remember opening with the "did you see that fight outside?" opener and this chick in the club totally looked at me like i was the biggest moron on the planet, so i have a long way to go with this. I guess i'll pm dre too while i'm at it.

This stuff does work with lesbians. But you have to keep in mind most of what is PUA comes natural to most girls.

Oh boy, I hope too many girls don't get in on our little secret! Ha.

But in all seriousness; in my experience, girls care more about grooming than genetics, and this extends to both sexes. I've talked to girls I've dated or just friends, and the women they point out as 'sexy' are the ones that are done up the most, and not necessarily have the greatest features or facial symmetry.
There is obviously a discrepancy among the lesbian community that are kinda butch and not caring at all about their appearance.

I know a couple lesbians, but haven't really seen them in action. However, I would recommend being outgoing, have a big smile, try to engage in brief (almost timid) eye contact, and definitely use a lot of kino. Make your target your friend, and touch her a lot. I would do with less negs and more compliments though than how men do it, since as a woman your social value would already be high...

A lot of this is just speculation so take it as you will.

Hobbit it would be awesome to be able to perfect a completely lesbian model of pickup i guess thats sort of my goal.
Nice advice Plethorma i'll keep that stuff in mind when i'm in the field...