What I always do is I always explain the rules of the game to her before we start and then I say to her 'before we start I got to know have you played this game before..?'. So, now you know whether she has played before or not

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By the way, I include two trick questions in mine:
1). (Pretend to genuinely forget and ask her on question four) 'So, how many questions was that?' She may answer right or wrong here.
2). If she answers right (i.e. truthfully) then you've got her! and no second question is needed. But if shes on to you and lies.. then go into the following:
'Damn! you're good!! are you seriously telling me you've never played this before?!?'
She'll prolly try and deny it 'no I've never...!!' ...and you've got her
And... If she outsmarts you both times she prolly deserves a drink!
Hope that helps and hope that makes sense too -I typed it out really quickly cos I've gtg.
Good luck