From what I've seen, it really depends on the situation. If you're walking up to people during Daygame or something similar, from my studies so far when you deviate from a question-opener, it mostly shifts to Direct-Game (whereas Question openers are a staple of Indirect-Game).
So you might say something like "Excuse me, but I just had to come over and say that you're the most beautiful woman I've seen today and I just had to talk to you. My name is ______." then continue stacking/gaming.
However, if you're at a party/club/etc, I've seen people (like Mehow, Lyons, and those typs) use very "typical" openers but the way they deliver is just so much better than 99.9% of the people that do.
For example, I've seen Mehow just open with "Woooo!" However, he says it in such a way where he's not a "performance monkey" (his words) but is also a very energetic, lively person so that the set he's opening will feel a very good vibe from him. Then he'll just start up a new thread.
That's what I've seen from my studies so far. I'm interested to see what others say, too.

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