| Given the sheer nature of her problem, I don't believe there IS a way for you to leave in a manner that will allow you to sort of stand her upright before you dash. She's gonna have to crawl out of that hole herself. I don't mean that to sound callous, like an "It's her problem" type of thing, but that the solution to this can't be provided by you or anyone else, and it's not--I guarantee--going to be you or anyone else who drags her out of that pit. Only she can do that. As someone who's spent many years battling depression to finally come out on the other side, I can look back down into that pit and tell you from experience that it's likely all you're doing is enabling her to continue with the way things are. If she's gonna get better, SHE'S gotta make that choice, because nobody else can make it for her, and it could very well be that the BEST thing you can do for her is to leave. In most cases, someone with depression, as with gambling or alcoholism or drug abuse, has to TRULY hit rock bottom before something finally screams to them that they need to turn things around. Don't quote me on it, but maybe your leaving could be the impetus she desperately needs.
In the event that it's not, and she does something rash after you leave, that's not your fault, and you cannot blame yourself, and you especially can't ALREADY begin assuming responsibility for hypothetical bad things you're afraid may happen in the future when you haven't even left yet. Just as she is the only one who can make the effort to get better, she is the only one who can make the choice to harm herself or others. That is NOT on you. It is NOT.
I definitely see some codependency here. Just as she always needs someone to fix things and hold her up, maybe you've developed an issue of always needing someone to fix. There's a movie called When a Man Loves a Woman where Meg Ryan (before she fucked her face up) plays an alcoholic married to Andy Garcia, and when her character hits bottom and enters detox and emerges a stronger, better woman, Garcia is the one who starts losing his grip because they lived so chaotically for so long that he doesn't know how to function without having to constantly control and manage his mess of a wife. Amazingly enough, they end up going to a marriage counselor to resolve HIS codependency on his alcoholic wife. It's a very eye-opening depiction of how when it appears that just one half of a couple has a big problem, both parties can feed off each other in the most unhealthy and invisible ways.
There's no "good" way to break up with somebody. Explain to her that it's time that you leave, and it's something you need to do for her and, more importantly, for yourself. Tell her that you love her and will always care about her but you have lost so much of your life and time and energy to the black hole of her depression and nothing ever seems to be enough to fill it, and you've begun to lose yourself in it. You've become so defined and constricted by this one aspect of your relationship that you're not even sure who you are or what you want anymore, and you need to go away and figure out your life again, and she needs to do the same. She has a very, very serious problem, but SHE has to be the one to take the steps to get over it. Be caring, but firm, and DON'T back down. She will cry. She may plead. DO NOT back down.
If she's not gonna go into counseling and take responsibility for herself (which will also be a very long, hard road), then your relationship is salted earth, and nothing's ever gonna grow there. Take what's left of yourself and leave, and perhaps consider picking up a weekly therapy session of your own to see if you are codependent on fixer-upper gals--because if you are and you don't start working to recognize and resolve it, you will find yourself dating the same girl over and over in many different guises.
You want better than that for your life, don't you? You know what you have to do.
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