i think u can number close in the two set...either by number closing both..or just one of them by asking for one of their numebrs but give ure phone to the target..(i havnt field tested these but others have)
as for k-close, ure right u need to isolate to do that..and the best way is with a wing..if u havnt got a wing go find a random guy in the club tell him theres a girl u wanna introduce..or some bullshit lol..then isolate...alternativly u could just go for a bit of the dual induction massage if you know what i mean

cheers