One of my favorite approach openers for sets with guys in them is..."Oh my God, where did you get that shirt man? I ask because I had one just like it and I lent it to my last girlfriend and she ran off with it. Its like I have to buy two of everything...

You know what I mean." Flat ignore the others in the set besides the guys. Open then and say things interesting to them. Sports, Cars, Alchohol, anything besides women talk. Disqualify yourself as a suitor, just be one of the boys. Then I quickly go to "So how does everyone know each other?" I need to know if the girl is a potential target or someone's girlfriend. From there decide if its worth it, and enjoy the opener.
"REMEMBER GUYS ARE JUST UGLY GIRLS!" ~ Mystery