At house parties people strongly tend to gather in groups of 3-6 people. In this case, after opening the set starting the routine with "How do you all know each other" as Mystery advocates, seems especially appropriate.
This is important because if you have bad luck and there's some AMOGs around. And since you're at a house-party where people probably know each other there is a possibility that there are several of their friends and you could get your ass kicked big time if youre not a little careful. If you watch out for that there's nothing that can go all that wrong if you use standard routines. be careful not to use the exact same routine here all the time, cause people in different sets will listen to you as you speak if you display sufficient alpha-characteristics and will pick up some of the stuff you got going in your routine. Try to do your routines a little slower so you got sufficient material to take you trough the night.
On the other side house parties are perfect because there tend to be a lot of socially remote locations in other rooms or upstairs or wherever to isolate your target at. There you can do all your little games (cube, cold reading or using your prop-bag) without showing it to everybody. This way you can re-use it several times in the same night.
Dont forget to social-proof yourself with the first or second set by taking a walk with some HBs around the location. Since quite some people will probably know each other here association and display of value is especially efficient!
Hope I could help a little
