LOL, if someone gives you some opener it will automatically become canned material, won`t it?
Use some situational stuff:
- observe interesting things in that location you are in and initiate conversation about it
- learn few cool things about history of the town/country you are in
- if gaming local girls, ask advice of cool places to go out
- if gaming other tourists, find out which are cool places to go and become a tour guide to them
Why would be vierd to game girls on vacation, it is perfect situation. Everybody is relaxed and want`s to have a great time, why would that be a problem?