First post (FYI)- Well I have been doing pickup for a few months now and I have officially submerged myself in it...

(you can use this on girls that you know a bit (like acquaintances and so forth) ...to tell you the truth I have not used this as an opener that I have never met)

The question is "what interesting thing I could talk about in mid game or even going right into the comfort level?" when online? (works even better face to face) Then it just randomly hit me...do a kind of a opener. Ask her a question only girls can answer.
aaand the question goes like this, your first hook her with "...I need an intelligent girl to answer my question...I'm kind of doing some research." second the question (of course)..."okay tell me how many text messages or wall posts do you get online from guys that just asks "how are you" or "how's it going?" and this question usually gets a girl pumped...

Note*-it is important that you did not say how are you or how's it going in past messages or on your past wall posts....

2nd note*- Also tell her that other girls have been asked this question! and that you have made bets on who was right and who was wrong.....and the bets could be like a date, her unborn baby, a million dollars...you get the point.

the questions generally portrays
A. That you're not one of those lame guys and you "get it"
B. It's a great conversation mid game opener and...this gives you a great opportunity to show her that you're an Alpha male.(giving her advices, meeting for a second time...etc)
C. Non-threatening...and gives the girl a chance to yap away while you neg her on some parts yet...get closer. (even works great on girls with Boyfriends)

The way I did it was I would ask her the question and she told me at least 3 stories very descriptively...and I gave her some Alpha Male advice and she wanted to go on chatting but I had to go. After I told her that I had to jet...she actually started apologizing to me.. for talking to me much! Then I ended it with "hey I gotta go my friends and I are going snipe hunting!" and this message made her leave me a wall post and a message on facebook...nice!

hopefully this helps...post on how it goes!

P.S. I am very curious to see if it works on random approaches..

I think that's a pretty solid idea. You are thinking outside the box and are developing your own ideas, which is superb

Thanks a lot abdul! Good hunting bud